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Police inquiries suggest it followed an incident on the Lettsome Estate in McNeil Road, Camberwell, Southwark, at around 8.30pm.
Both men are in a serious but stable condition and remain in hospital undergoing treatment.
Officers are appealing for witnesses, or anyone with information, to contact police on 101 citing reference 5962/31DEC22.
Information can also be provided to the independent charity Crimestoppers anonymously online or by calling 0800 555111.