Oluwamayowa Adeyemi, 21, known as Samson, was gunned down in Brackenfield Close in Hackney, close to midnight on June 5. He was pronounced dead at the scene as police and ambulance workers arrived.
Three men were arrested on suspicion of being connected to the murder over the following week and released on bail.
And officers have taken two further suspects, both in their twenties, into custody on suspicion of perverting the course of justice and possessing a firearm. Both have been released on bail until July.
The arrests come as police appeal for more information on a Volvo that was abandoned nearly two miles from the scene of the murder, with the false registration plate EX18 EXE.
Detective Chief Inspector Paul Considine, leading the investigation, said: “Although we have made arrests, the Volvo remains a very important appeal point for us.
“It was found abandoned the morning after Samson was shot. When it was discovered by police, it was bearing a false registration plate and therefore, in the days and weeks beforehand, may have been displaying different plates.
“The car is a large estate vehicle and had some distinguishing features – there were scuff marks to both corners of the front bumper and the front passenger door mirror was held on with tape.
Mr Considine added that he wanted to hear from anyone who witnessed the shooting or who has any other information.
He went on: “This is a tragic incident that has resulted in the loss of a young man’s life, and robbed a family of their future together, leaving them devastated. If you can help us find those responsible, please don’t hesitate to get in touch.”
Anyone with information is asked to contact the incident room on 020 8345 3865, call 101 or tweet @MetCC and quote CAD 8894/5June or Operation Scalby
Alternatively, you can provide information anonymously to the independent charity Crimestoppers on 0800 555 111.